I’m sure there’s meta on it already somewhere (likely on old LJ communities?) but I would be very interested in reading an analysis on why John, Sam, and Mary are all associated w/ yellow eyes at some point—John actually being possessed by Azazel in 1x22; Dean’s hallucinations of Sam in 4x06 and Sam’s hallucination in 4x21; Heaven!Mary talking to Sam & Dean in 5x16—while Dean never is.
Rewatched 6x01 and Gamble is very clear in this ep that Azazel = generational family trauma, and of Dean’s fear of that trauma / harm / horror happening again. Which both very much fits w/ how the Azazel/yellow eyes are used in Kripke’s era around Mary, John & Sam, and makes sense why Gamble then focused on Dean for S6.