I recently stumbled across a theory that Bee isn’t even the ORIGINAL Bee, she’s just a robot her father created to replace the real human Bee who presumably died years and years ago (Bee did say in the birthday episode that she got really sick one time, so there’s actual canon evidence to back this up). Honestly I really dig this one bc the angst potential is huge, it really fits into canon so well regarding Bee’s general behavior and how others view her. And her being a robot is already so isolating for her, but imagine if she’s just a replacement--that’d probably make her feel even more out of place than anything, which is why she connects with Puppycat so well.
Also tying this into the reboot, if the Bee that Puppycat babysat for a day was the original human Bee, that would make things SO sad. Imagine being on the run in a “monstrous” form for years and finally returning to one of the planets you feel safe to hide on...only to find out that the girl you once looked after is dead and has been replaced with a robot. And that robot is well aware that her entire existence is a feeble attempt at preserving what once was, that she’s not human, that she’ll never live up to the original human version of herself. Oof.
Maybe Puppycat originally decided to stay with her out of pity, but over time grew to really care about her as her own person. And I feel like Bee would definitely appreciate that 🥺