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Script Shrink

@scriptshrink / scriptshrink.tumblr.com

Writing about mental illness? Ask ScriptShrink!
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scriptshrink
Anonymous asked:

Hey Shrink! I was trying to figure out what medications my bipolar character should take, and I noticed that there are a bunch of epilepsy meds listed! What gives??

Weirdly enough, that’s because the bipolar and epilepsy are actually kinda similar! Basically, we think they’re both related to instability in the neurons in your brain.

In epilepsy, the neurons will sometimes suddenly all go into overdrive in a relatively short amount of time (ie minutes).

In bipolar, we think that the neurons go through phases of increased and decreased activity compared to baseline. The fluctuations in bipolar are nowhere near the intensity seen in epilepsy, but they’re much longer term (ie weeks-months).

Anticonvulsants (also known as neuromodulators or mood stabilizers) work by keeping the neurons from getting too far away from their level of normal activity - whether it’s the sudden spikes from epilepsy or the long-term bipolar cycles.

Note - These are all currently just theories. We’re still not 100% sure exactly how this actually works. Brains are very complicated.

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everentropy

We don’t quite know how lithium, one of the oldest treatments for bipolar, works and it’s been in use for centuries

Yep! It’s one of the mysteries of psychopharmacology I’d really like to see solved.

[Image description: A tumblr reply from scix-in-the-back-row stating: “Centuries?????”]

Technically, yes. Lithium was first used to treat mania as early as the 1870s. However, it fell out of fashion for a while until the 1950s. [Source]

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scriptshrink
Anonymous asked:

Hey Shrink! I was trying to figure out what medications my bipolar character should take, and I noticed that there are a bunch of epilepsy meds listed! What gives??

Weirdly enough, that’s because the bipolar and epilepsy are actually kinda similar! Basically, we think they’re both related to instability in the neurons in your brain.

In epilepsy, the neurons will sometimes suddenly all go into overdrive in a relatively short amount of time (ie minutes).

In bipolar, we think that the neurons go through phases of increased and decreased activity compared to baseline. The fluctuations in bipolar are nowhere near the intensity seen in epilepsy, but they’re much longer term (ie weeks-months).

Anticonvulsants (also known as neuromodulators or mood stabilizers) work by keeping the neurons from getting too far away from their level of normal activity - whether it’s the sudden spikes from epilepsy or the long-term bipolar cycles.

Note - These are all currently just theories. We’re still not 100% sure exactly how this actually works. Brains are very complicated.

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everentropy

We don’t quite know how lithium, one of the oldest treatments for bipolar, works and it’s been in use for centuries

Yep! It’s one of the mysteries of psychopharmacology I’d really like to see solved.

Avatar
Anonymous asked:

Hey Shrink! I was trying to figure out what medications my bipolar character should take, and I noticed that there are a bunch of epilepsy meds listed! What gives??

Weirdly enough, that’s because the bipolar and epilepsy are actually kinda similar! Basically, we think they’re both related to instability in the neurons in your brain.

In epilepsy, the neurons will sometimes suddenly all go into overdrive in a relatively short amount of time (ie minutes).

In bipolar, we think that the neurons go through phases of increased and decreased activity compared to baseline. The fluctuations in bipolar are nowhere near the intensity seen in epilepsy, but they’re much longer term (ie weeks-months).

Anticonvulsants (also known as neuromodulators or mood stabilizers) work by keeping the neurons from getting too far away from their level of normal activity - whether it’s the sudden spikes from epilepsy or the long-term bipolar cycles.

Note - These are all currently just theories. We’re still not 100% sure exactly how this actually works. Brains are very complicated.

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Anonymous asked:

For treatment team meetings then, do pharmacists not typically attend?

Not at my internship site, no. Evidently they used to have a pharmacist specifically for the ward, but they no longer have one here. All medications are administered by the nurses.

This is something that is likely to vary depending on the site.

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I'm writing about a character suffering from Major Depressive Disorder and I had a question about medication combinations. In the story her psychiatrist and her therapist by proxy become worried that the combination of medications she's on might be causing an increase to her anxiety or desire to self harm and want to change what she's taking. Is this a realistic situation? What medications could she be on? Thank you!!

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CW: self-harm, suicide

Yes, totally possible. While antidepressants are often used to treat anxiety disorders, they can also cause symptoms related to anxiety too. It’s most frequently described as jitteriness, but there are more symptoms associated with it as well (scroll down to table one here).

 Two drugs are especially associated with causing anxiety: imipramine (Tofranil) and fluoxetine (Prozac). Of those two, I would lean towards Prozac, as it’s considered a first-line treatment and is extremely common. Tofranil is a bit outdated and rarely used anymore.

Note - Typically the anxiety occurs within the first few weeks of treatment, and it actually does go away fairly quickly. A psychiatrist may try to see if the anxiety symptoms go away before switching to a different drug. 

Now, the self-harm is a bit of a different story. All antidepressants may potentially increase the risk of suicidal tendencies in children, adolescents, and young adults (ie under the age of 25 or so). 

Because this question was sent off anon, the Shrink asked how old this character is, and she’s 17. A psychiatrist could easily see an increased desire to self-harm as a warning sign that this specific antidepressant may be making your character suicidal. That’s definitely enough to merit changing what medication she’s on!

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scriptshrink
Anonymous asked:

Why might one antidepressant be prescribed over another? For example, why might a patient take Prozac over Wellbutrin or vice versa? Thank you love your blog!!

There are a lot of factors!

  1. What specific symptoms are being treated (certain drugs treat certain symptoms more effectively)
  2. What side effects the drugs have / what the character is willing to put up with
  3. What medications the prescribing doctor is the most familiar with.
  4. Patient factors (how old they are, what they’ve taken in the past, what they’re currently taking, their medical history / comorbid disorders, if they are or want to become pregnant, etc.)

Three random examples of things a psychiatrist could consider, off the top of my head:

If someone has insomnia as part of their depression, they might be prescribed Remeron / Mirtazapine (to be taken at night) because it is likely to help them sleep.

If a character also has ADHD, Strattera / Atomoxetine might be an option.

One class of antidepressants, MAO inhibitors, are almost never prescribed without the patient trying a lot of other antidepressants first. This is because you have to follow an extremely strict diet or risk death. And by “strict diet” I mean that you can’t eat cheese, cured or processed meats, anything with soy, or drink beer (among many other things). If the character is willing to put up with that diet, and nothing else has worked for them so far, MAOIs might be an option; otherwise, they’re not going to be prescribed.

There are literally hundreds, if not thousands, of little things like that to consider when prescribing psychotropic medications. That’s why they pay psychiatrists the big bucks.

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An anon pointed out that the qualities of the drug itself matter! For instance, some drugs need to be taken at the exact same time of day to be effective; some drugs also need to be taken multiple times a day!

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Anonymous asked:

Why might one antidepressant be prescribed over another? For example, why might a patient take Prozac over Wellbutrin or vice versa? Thank you love your blog!!

There are a lot of factors!

  1. What specific symptoms are being treated (certain drugs treat certain symptoms more effectively)
  2. What side effects the drugs have / what the character is willing to put up with
  3. What medications the prescribing doctor is the most familiar with.
  4. Patient factors (how old they are, what they’ve taken in the past, what they’re currently taking, their medical history / comorbid disorders, if they are or want to become pregnant, etc.)

Three random examples of things a psychiatrist could consider, off the top of my head:

If someone has insomnia as part of their depression, they might be prescribed Remeron / Mirtazapine (to be taken at night) because it is likely to help them sleep.

If a character also has ADHD, Strattera / Atomoxetine might be an option.

One class of antidepressants, MAO inhibitors, are almost never prescribed without the patient trying a lot of other antidepressants first. This is because you have to follow an extremely strict diet or risk death. And by “strict diet” I mean that you can’t eat cheese, cured or processed meats, anything with soy, or drink beer (among many other things). If the character is willing to put up with that diet, and nothing else has worked for them so far, MAOIs might be an option; otherwise, they’re not going to be prescribed.

There are literally hundreds, if not thousands, of little things like that to consider when prescribing psychotropic medications. That’s why they pay psychiatrists the big bucks.

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Anonymous asked:

I have a few questions I was hoping you could answer! :) What do you feel is one of the most common misconceptions you see in writing about therapists/psychologists/psychiatrists? Also, in a character with severe C-PTSD who would be best for them to see out of the three? Is it possible to see more than one? How often would one of the above see someone with severe C-PTSD? Would twice a week be excessive? Not enough? etc. Thank you for your time and providing us all with so much info!

I’d say one of the misconceptions that really pisses me off is the idea that all therapists are Freudian. I really hate Freud.

For intense trauma work, meeting with a psychologist twice a week is pretty reasonable.

With severe mental illnesses, it’s typically recommended to see a psychiatrist in addition to a psychologist in order to be prescribed medications. A character would typically see a psychiatrist roughly once a month or so (less often if the character has remained stable on their medications). CPTSD and PTSD are a little squidgy because there aren’t really medications that deal specifically with those disorders, but sometimes SSRIs or a drug like Prazosin would be prescribed.

For the rest of your questions, I’ve got a few posts in my archives that I think you should check out!

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Personal Experience: Medication “Experiments”

Randomly thought of this because of recent events in my life, and if this has been said/is too much of a rant please delete and ignore, but I just remembered that doctors are weird about “experimenting”.

I took Zoloft for my bipolar for roughly five years. It gradually started to lessen in effect, even as we upped my dosage. So we switched to a different medication, can’t remember the name, that completely muffled my mania. It either made me depressed, or my depression finally had a chance to shine, but either way, it wasn’t right. I hated it, I wanted off, I wanted a different medication. My doctor decided to add an antidepressant instead, because I was a minor and had no say over what I took. The antidepressant helped a little, but it made me so “blah” that everyone noticed. Even the kids at school, who usually avoided me, started to notice something was different. And according to the doctor, that was what normal people felt like (yes, she said normal, which is a great thing to say to a depressed, suicidal child who feels alienated from his peers already). Normal was blah. Normal was empty. Normal was wanting to die but being too afraid to do it.

We switched psychiatrists. The new doctor took me straight off the meds I was on (no weaning, just told me to stop taking them) and said “we’ll have to experiment”. That’s also around the time I learned that I was always being put on new things. Nothing tried and true, just the newest drugs they could get their hands on. Stuff they didn’t know what the effects would be. And all adverse effects were met with “We’ll wait and see if it gets sorted out.”

This all came to the front of my mind because we changed my meds again just this month. My doctor is taking me off Abilify (finally a drug that didn’t give side effects, but still stopped working), which I’ve only been on for a few months, and putting me on Latuda. We’re also increasing my anxiety medication. He’s the only psychiatrist I’ve had who’s been careful about choosing my meds, but it’s still scary to hear the word “experiment” coming from a doctor.

So to anyone looking to write someone who’s been on and off a lot of meds, please remember that it’s just. So exhausting. So scary. So infuriating. And the words doctors choose affect the way you view medication your whole life.

[[It’s been a while since I got a submission! Thank you for sharing your personal experiences - Shrink]]

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Anonymous asked:

How to do I write a character with Insomnia? Like some general guidelines on what to do and not to do.

Here’s a few guidelines:

  1. Keep in mind that there are multiple kinds of insomnia.
  2. Initial insomnia (sometimes called onset insomnia) - the character has trouble falling asleep.
  3. Middle insomnia (sometimes called maintenance insomnia) - the character has trouble staying asleep, frequently waking up during the night.
  4. Late insomnia (aka terminal insomnia) - the character wakes up a lot earlier than they meant to, and is unable to fall back asleep.
  5. Long term insomnia has really negative effects on your character’s body and mind.
  6. Insomnia is frequently comorbid with, or even a symptom of, other mental disorders.
  7. Medications are not a cure-all. 
  8. Your character can build up tolerance to hypnotic medications quickly (some in as little as three days!) and while they do make you sleep, the sleep you get is not as restful. These kinds of medications can also be addictive.
  9. Over the counter sleep medications do not work for insomnia - they can make you drowsy but do not actually affect how much sleep you get.
  10. Melatonin isn’t addictive and can be slightly/moderately effective, but it’s best with people doing shift work or dealing with jet lag, not as a daily thing.

Hope that helps!

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scriptshrink
Anonymous asked:

What do anti-psychotics do to people who aren't hallucinating? What happens in the long term? What if you suddenly stop taking them? My character is 28 and has been on anti-psychotics since he was 14 because he actually was seeing monsters but obviously nobody believed him and thus, drugs. If he stfu and took the pills (because due to Plot, they actually did mute the monster thing significantly), how likely is it he'd still be on them at 28? What would happen if he suddenly went cold turkey?

Being honest, Anon, your character is looking at some serious side effects. Here are some of the most notable / dangerous ones:

Involuntary movements:

  • Muscle spasms
  • Feelings of inner restlessness
  • Parkinsons-like symptoms
  • Tardive dyskinesia (which is irreversible, even if your character stops taking the medication!) I can go into TD in more detail if y’all want - I did a presentation on it recently!

Metabolic:

  • Weight gain 
  • Type II diabetes

Other important side effects:

  • Sedation (often extreme)
  • Increased chance for arrhythmia (with specific drugs)

And those are just the really serious ones! There’s a lot of other different ones too.

Certain classes of antipsychotics are more associated with different symptoms. For instance, the typical antipsychotics are more associated with movement symptoms, and atypical ones with metabolic ones. That’s not to say that an atypical antipsychotic can’t cause movement symptoms - it just does so at a much lower rate than a typical antipsychotic does.

Something really important to note - your character would likely not be on antipsychotics continuously for 14 years straight. Usually, a year or two after the first episode of psychosis, they’ll try to taper down and see if the antipsychotic is still necessary. If they have another episode, they’d go back on it, and they’d reevaluate after 3-5 years.

Oh, another thing - nowadays a lot of people taking antipsychotics long term actually don’t take pills; they get an injection. How frequently they get the shot depends on the drug, but it ranges from once every two weeks to once every three months.

Going cold turkey will indeed cause withdrawal symptoms - these symptoms are more specific to the drug in question.

Hope this helps!

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vorpalgirl

@scriptshrink question - I was told (by a psych prof, but years ago) that (at least one, probably old-school?) antipsychotic could CAUSE hallucinations in people who don’t normally experience them (specifically, it would have been in reference to something that at least previously was common to use for schizophrenia and will have been around for decades. I think we were discussing a portrayal in a film – this prof loved to use popular culture examples, usually movies, and discuss and deconstruct them with us for what was realistic/plausible or not, a sort of way to get us to think critically and diagnostically while correcting popular misconceptions –  specifically, the film was A Beautiful Mind, where a schizophrenic character is given an injection, and he within minutes responds like he’s been sedated. I remember the prof showing us this scene and commenting that the medication he was being given in the scene “wouldn’t do that to a non-schizophrenic”, and…that’s about the time I remember learning about the weird effect such a thing might have on non-psychotic folks?).  Anyway. tldr, I notice that symptom’s not on the list though, so needless to say I’m curious and wondering where this idea came from and if it’s maybe medication-specific or if it’s just…not true (I don’t THINK I’m misremembering or misheard him, but I want to be sure)

Without knowing the drug in question I cannot say for sure, but generally* no, antipsychotics do not directly cause non-schizophrenic people to experience hallucinations.

Antipsychotics (especially atypical ones) are actually starting to see use in treating mood disorders like bipolar I & II or severe depression - even without psychosis ever being present. They wouldn’t be used if they induced psychosis.

I am really not sure where your professor got “non-schizophrenic people won’t experience sedation when taking antipsychotics” because they absolutely will.  We use injections of antipsychotics (usually Haldol, Zyprexa, or Geodon) at my internship site when a patient becomes violent and all efforts to de-escalate or redirect the patient have failed. I obviously cannot go into detail to protect patient confidentiality, but suffice it to say that it is effective regardless of diagnosis.

* Note - I say “generally” because I don’t want to say it has never happened, but if it does it’s at such an extremely low rate that it’s not even really worth mentioning.

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Anonymous asked:

How do doctors prescribe depression medication? Say, for instance, a young male, mid-20s, develops resistance or gets used to medication fairly quickly. Would the doctor prescribe a higher dosage each time, or would they wean him under supervision and then continue the same dosage?

When a psychotropic medication isn’t working, there are a couple of different options. 

  • Increase the dosage and see if it starts working.
  • Taper off of the drug and try a different one.
  • Add another drug in addition to the current prescription.

Which is chosen depends on the doctor; there’s benefits and drawbacks for each option.

Typically, if a character developed tolerance to a medication quickly, and increasing the dosage did not work, they would not be tapered off and put back on it. There are a lot of other antidepressants out there (~30 FDA approved medications for treating depression, and god knows how many other drugs that are prescribed off-label for it), so it doesn’t make sense to waste time putting your character back on a medication that they already know won’t work for very long.

And as an FYI, when someone has severe depression that’s resistant to many different medications, ECT might be recommended as a treatment.

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Anonymous asked:

What do anti-psychotics do to people who aren't hallucinating? What happens in the long term? What if you suddenly stop taking them? My character is 28 and has been on anti-psychotics since he was 14 because he actually was seeing monsters but obviously nobody believed him and thus, drugs. If he stfu and took the pills (because due to Plot, they actually did mute the monster thing significantly), how likely is it he'd still be on them at 28? What would happen if he suddenly went cold turkey?

Being honest, Anon, your character is looking at some serious side effects. Here are some of the most notable / dangerous ones:

Involuntary movements:

  • Muscle spasms
  • Feelings of inner restlessness
  • Parkinsons-like symptoms
  • Tardive dyskinesia (which is irreversible, even if your character stops taking the medication!) I can go into TD in more detail if y’all want - I did a presentation on it recently!

Metabolic:

  • Weight gain 
  • Type II diabetes

Other important side effects:

  • Sedation (often extreme)
  • Increased chance for arrhythmia (with specific drugs)

And those are just the really serious ones! There’s a lot of other different ones too.

Certain classes of antipsychotics are more associated with different symptoms. For instance, the typical antipsychotics are more associated with movement symptoms, and atypical ones with metabolic ones. That’s not to say that an atypical antipsychotic can’t cause movement symptoms - it just does so at a much lower rate than a typical antipsychotic does.

Something really important to note - your character would likely not be on antipsychotics continuously for 14 years straight. Usually, a year or two after the first episode of psychosis, they’ll try to taper down and see if the antipsychotic is still necessary. If they have another episode, they’d go back on it, and they’d reevaluate after 3-5 years.

Oh, another thing - nowadays a lot of people taking antipsychotics long term actually don’t take pills; they get an injection. How frequently they get the shot depends on the drug, but it ranges from once every two weeks to once every three months.

Going cold turkey will indeed cause withdrawal symptoms - these symptoms are more specific to the drug in question.

Hope this helps!

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Hi! Thanks for everything you do :) If a guy with bipolar is put on medication that sends him towards mania, would his doctor keep him on the meds to see if he even out, or would he immediately be taken off them? Thanks in advance!

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From the Shrink’s impression, mania’s pretty much considered an emergency. The symptoms of a full manic episode are severe enough that they wouldn’t be kept on the medication.

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Anonymous asked:

What are some of the most expensive medications used to treat mental disorders that have to be taken on a daily basis?

I’m going off the assumption that you’re talking about America, home of the not-free healthcare. I’ve taken these prices from https://www.goodrx.com using my location. Prices will vary by area.

All of the following assumes your character is taking the maximum recommended dosage, and all numbers are rounded because math gives Shrink a headache.

The most expensive daily medication (ie. not a monthly injection) that I could find is Aplenzin, an antidepressant, which can roughly cost $125 a pill, which means your character would be spending ~$46,000 a year. Some other notable runnerups are: Emsam (~$52 per patch, ~$19,000 a year), Saphris ($20 a pill, twice a day, ~$14,600 a year), and Rexulti ($33 a pill, ~$13,000 a year).

That’s the raw, uninsured, cash price. Many people who have insurance will not be paying that full price. For instance, one of the Scriptshrink consultants would be paying $300 a month for their prescriptions, but with insurance the monthly cost is only $5. However, insurance is very very complicated and getting money from them can be like getting blood from a stone.

After a certain amount of time, drugs also get ‘generic’ versions. These versions are a lot cheaper, but may have slight differences from the name brand. Another ScriptShrink consultant’s medications, if they were name brand, would cost about $2,000 a month. The generics cost $545 a month (before insurance).

There’s also something called “patient assistance programs” that provide medication at lower cost to people in need, either through a nonprofit or the manufacturer directly. That would significantly reduce the prices.

Another thing to note - it’s really likely that people with severe mental illness take multiple medications at once. Individual medications might not have that big ol’ price tag that Aplenzin et al. have, but the prices stack up.

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Hello, hope you're well! :) Question about Brief Psychotic Disorder. Character is traumatized by having to face his abuser and his manipulation/mental abuse daily. Character is an addict, and, in the throes of the psychotic episode, relapses into abusing Xanax/Valium/Vicodin and the like to deal with the stress. Would that stop the psychotic episode, since it 'helps' him feel less anxious/scared/stressed and 'feel less' traumatized? Or is it not that simple?

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From what I can tell, it’s really not that simple. These medications may help the character feel temporarily better and less stressed out, but it would not end their psychotic episode. You’d typically need antipsychotics for that.

However, because your character has brief psychotic disorder, not schizophreniform, schizophrenia, etc, it’s possible that by the time an antipsychotic could kick in, the psychosis could already have ended. Sometimes they can kick in within a few days; other times it can take 6 weeks for the effects to kick in (to qualify for a diagnosis of brief psychotic disorder, the episode can’t last more than 4 weeks).

Disclaimer - psychopharm is not my forte, at all - @scriptpharmacist may help you get a better answer.

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