When fandoms collide...
How about a Loki - Pacific Rim AU?
Could be one of the various timelines! The kaiju are actually beasts from a mysterious place (probably Kang doing shenanigans in this timeline). They’re being sent to take over Midgard and the other 9 realms. Loki is sent, along with Thor, as ambassadors to Midgard to help since Asgard has technology that can help. Eventually, with Loki’s help, there are some jaegers developed that run on magic (thank you @voxmyriad for that bit of inspiration! ) and the pilots of those need to have a non-magic co-pilot for hand-wavy reasons. Loki had one, lost one, then, through a series of convenient events, they discovered a J-tech named Mobius might potentially be drift compatible with Loki Loki, of course, scoffs at the idea and a beautiful partnership is born
I imagine Sylvie and Verity (Hunter-B15) another jaeger pilot pair
OB and Casey as a J-Techs for Loki/Mobius and Sylvie/Verity respectively
Of course Hermann and Newton are there still as the K-science team cuz I can't not have them, along with our favorite characters from Pacific Rim and Loki