If man were merely a random product of evolution in some place on the margins of the universe, then his life would make no sense or might even be a chance of nature. But no, Reason is there at the beginning: creative, divine Reason. And because it is Reason, it also created freedom; and because freedom can be abused, there also exist forces harmful to creation.
Pope Benedict XVI, Easter Vigil Homily, full text http://www.catholicnewsagency.com/news/pope-benedict-easter-brings-us-to-the-side-of-reason-freedom-and-love/