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Biomedical Ephemera, or: A Frog for Your Boils

@biomedicalephemera / biomedicalephemera.tumblr.com

A blog for all biological and medical ephemera, from the age of Abraham through the era of medical quackery and cure-all nostrums. Featuring illustrations, history, and totally useless trivia from the diverse realms of nature and medicine. Buy me a coffee so I can stay up and keep the lights on around here!
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Three dog skulls from ‘Secrets of Bones’ hosted by Ben Garrod. The first image shows a regular dog skull; this contains both collagen, an organic compound, and calcium phosphate, a mineral compound.

In the images with the red gloves, another skull has been left in an oven for a few days. This has taken out all of the organic compounds, leaving just the mineral compounds. As you can see, this bone is too brittle to be of structural use.

In the images with the blue gloves, a skull has been soaked in formic acid for over a month. This removed the calcium phosphate from the bone but leaves the collagen. The surprising result is a very flexible skull.

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bonedahlia

Whaaaat. That is awesome.

If you haven’t seen ‘Secrets of Bones’ I’d highly recommend it. Here are links to the episodes on YouTube:

GO. Watch. Because I said so, that's why!

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Anonymous asked:

Your view on the YouTube channel the BrainScoop???

I love Emily Graslie and her enthusiasm is inspirational to me…pathology and anatomy is one of my favorite subjects, and she’s managed to explain things I’ve wanted to cover in much more succinct language than I’ve ever been able to come up with.

It’s sort of disheartening to me that I’ve never had that same continual enthusiasm for my education, and that she’s younger than me but much farther along in life than I am, but I still love all of her videos. They’re educational, fascinating, and sometimes extremely gross, and are part of one of the most interesting sets of channels on YouTube.

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Scientific Terminology: Taxonomy and Nomenclature 101

The origins of medical terms are interesting enough, but Greek and Latin roots are used throughout the sciences, and around here, you'll see them a lot when it comes to species names. There are some interesting ones out there, with some bizarre (and sometimes humorous) meanings...

But first! Some taxonomy basics:

Setting aside phylogeny-specific nomenclature and cladistics for now, Linnaean taxonomy is the system of naming species that has been used since, well, Carl Linnaeus. A "taxon" (plural taxa) is simply a grouping of one or more organisms, judged to belong to the same unit based on any number of qualifications. 

Though current "Linnaean taxonomy" (which is what's commonly used in schools and in general literature) differs significantly from Linnaeus' original three-kingdom, five-level, ranked classifications, it's still known by that name and takes many of the concepts from it, such as hierarchical classification. Thanks to the popularity of Linnaeus' 1735 work, Systema Naturae, a solid foundation for modern taxonomy was put in place, with an organized system, and short, understandable, scientific names.

Taxonomy today:

Currently, animal species are organized according to rules set down by the International Code of Zoological Nomenclature, to ensure uniformity across the zoological community. Plants and bacteria follow different naming codes, but those are less relevant here.

This is a basic schematic demonstrating the hierarchical system that's used when we classify a species:

According to the ICZN, the basic rank is that of species. The next most important rank is that of genus: when an organism is given a species name it is assigned to a genus, and the genus name is part of the species name. Species and genus were both seen by Linnaeus as "God-given"/"natural". Anything above genus was considered a construct made by man to more easily classify the world around him.

The third-most important rank, although it was not used by Linnaeus, is that of family. Even though family is important in understanding the classification of an animal, it is not used in the "scientific name", nor are any of the higher levels in its classification.

So what's a "scientific name?"

The italicized names that you see in scientific literature (and around here) refer to the specific species of a creature, and are called the binomen; that is, "two names". Those two names are the genus (first, and capitalized) and the species (second, never capitalized, even when named after a proper noun). An example of a binomen would be Choloepus hoffmanni - the genus is Choloepus, the two-toed sloths, and the species is Choloepus hoffmanni, Hoffmann's two-toed sloth.

Sometimes there are three names, or the trinomen of a creature. These tell you, first, the genus, second, the species, and third, the subspecies. Take the trinomen Choloepus hoffmanni pallescens. The genus is Choloepus, the species is Choloepus hoffmanni, and the subspecies is Choloepus hoffmanni pallescens, the Peruvian two-toed sloth.

Though you only are told the two (or three) most specific taxonomic groupings for a creature, you can use those (and a phylogenetic tree) to figure out all of the less-specific (Linnaean) taxa it belongs to, such as its Family, Order, Class, and Phylum.

What does the scientific name actually mean, though?

Often, the scientific name describes notable or distinguishing characteristics about a species, that you can decode (scientific terminology time!). Let's take the species Cyclopes didactylus. The first name given tells us that this creature belongs to the genus Cyclopes - "Circle-foot". Within that genus, the species name is Cyclopes didactylus (abbreviated C. didactylus after the first use), and yes, you do repeat the genus name in the species name, by ICZN guidelines. On its own, "didactylus" can be broken down to the roots of di-, dactyl, -(o)us. "Having two fingers." So the binominal can be deciphered as "Circle-foot having two fingers."

Circle-foot two-fingers! (aka the Silky or Pygmy Anteater)

This descriptive-type species name is not the only way scientists assign taxa, though.

For everything above genus, the taxa are fairly regulated/already-determined, are not easy to add and subtract from, and have strict naming guidelines. From genus on down, though, so long as what you've discovered is verified as a new species (or group of species falling together as a genus), congratulations! You have the honor of naming it. Well, assuming it's not patently offensive, vulgar, or unpronounceable. The ICZN approval board or the equivalent for your field has final say on whether or not a species can be given a submitted name.

Still, there are many ways to name a new species. You can name it in reference to physical characteristics, location found, a specific person or group, or even an ironic joke or pun. Look at the name Linnaeus gave the Blue Whale: Balaenoptera musculis. Balaenoptera = "Baleen-winged", ok, they have huge fins and baleen, so that makes sense.  Musculis = "little mouse". Har har har.

"Musculis" can also refer to "muscle," but given that Linnaeus was given to puns and double-meanings, he was well aware of the "little mouse" definition.

Notes:

**Though the specific epithet for a species can be used in more than one genus, genus names must remain absolutely unique, in accordance with ICZN rules. Ex. Since you can have more than one species with the didactylus epithet, Cyclopes didactylus and Inimicus didactylus are both valid names - though you really don't want to mix up the silky anteater with the "devil stinger"/lumpfish.

**When the specific species is not known, the abbreviation "sp." is used after the genus name. Ex. Lutra sp. refers to either Lutra lutra OR Lutra sumatrana, but it's unknown as to which one. When multiple species within a genus are being referred to (or the specific species is unimportant), the abbreviation "spp." is used after the genus name. Ex. Lutra spp. refers to BOTH Lutra lutra AND Lutra sumatrana.

Additional resources:

Source: msu.edu
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Medical Terminology: Latin and Greek Roots - Quantity and Position

Some more Greek and Latin roots today! LEARN THINGS! Two important subjects in medicine that are often used in terminology are quantity (both relative and specific) and position. These obviously tell you how much of something is being referred to and where something is happening...you could probably figure out what they all mean, but they're good to know the exact definition of!

Quantity:

Iso-/Equi-: Equal (ex: isomer - chemical compounds with different structures, but the same molecular formula, equivalent - very similar or exactly the same in value)

Poly-/Multi-: Many, much, multiple (ex: Polyester - a fabric whose polymers [a multiple-unit chemical chain] are linked together by ester bonds, multicolored - having many colors)

Hemi-/Semi-/Demi-: Half, roughly half, incomplete (ex: Hemisphere - one half of a sphere [such as the earth], semi-aquatic - a species that spends at least half of its time in the water, demitasse - the half-cup that strong black coffee is served in after meals)

Olig(o)-/Pauc(i)-: "Few", small amount (ex: Oligarchy - a government run by just a few people, paucity - a scarcity or small amount of something)

Dipl(o)-/Dupli-: Double (ex: diploid - a cell with two of each type of chromosome in it - body [somatic] cells of humans are all diploid)

Haplo-: Single (ex: haploid - a cell with one of each type of chromosome - sex cells [gametes] have one of each chromosome, they need to meet up with another sex cell in order to become diploid and become able to form body cells)

Position:

Peri-/Circum-: Around, surrounding (circumcision - to cut around, pericardium - around the heart)

Sinstr-/Laev(o)-/Levo-: Left, to the left of

Medi-/Mes(o)-: Middle, median

Dextr(o)-/Dexi-: Right, to the right of

Cata-: Down, downward (ex: catarrh - a flowing down/inflammation of the mucus membranes)

Dia-: Through, completely, across (ex: diagnosis - knowing completely - determining the cause of a disease, diarrhea - flowing through- downward fluid discharge)

En-/Em-: Within, in (ex: encephalon - in the head - refers to the brain, embolism - thrown in - refers to a plugging of a vessel by an object travelling through the blood stream, usually a clot)

Palin-: Back, backwards, repeat, again (ex: Palindrome - something [usually a word or number] the same both backward and forward, palinesthesia - the return of sensation)

Further Reading/Sources:

And, of course, Antiquus Morbis

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Medical Terminology: Latin and Greek Roots

Now for some of the fun terms! These may be out of alphabetical order, so my apologies there. This is just a short selection of some common and interesting terms; more will come soon. These terms will also be re-organized when I finish the next two posts.

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pachy-: A thickening of the skin - pachyderma is a thickening of the skin, and pachydermata is an obsolete class of mammals with thick skin...elephants and their close kin are still often referred to as "pachyderms" in non-scientific literature.

path(o)-/-pathy: Disease, pertaining to a disease or disorder (ex: pathologist, neuropathy)

pyro-/pur-: fever (from pyro - fire, but you probably already guessed that!) 

-exia/-exic: appetite, habit or state, to be in a condition

-mania: "Mental derangement characterized by excitement or delusion", craze, insanity, passion, spirit

dys-: abnormal, wrong, painful, difficult

-plasy: "development of"

phos-: Pertaining to light and its chemical properties (when not used in terms of phosphorescence, this is a nearly completely archaic root)

ec-/ex(o)-: Out, outside of, away from

myco-: Pertaining to fungus (don't confuse with myo - pertaining to muscle, or myx(o)- pertaining to mucus!)

-oid: "Resemblance to" (ex: Mongoloid...the mentally deficient apparently looked like what people thought Mongols looked like)

para-: Along side of, abnormal

-pexia: Fixation upon

sangui-/sanguine: Pertaining to blood

sclero-/-sclerosis: Hardening, hardening of the skin

sinistr(o)-: left, left side (nice how "sinister" comes from the term for the left side, eh southpaws? ;D)

somat(o)-/somatico-: Body/bodily

tetan-: Stiff, rigid, tense

trans-: Denoting something as moving or situated "across" or "through"

-trophy: Nourishment, development

viscer(o)-: Pertaining to the internal organs, the viscera

sync-: "To be in agreement with"

-uria: Pertaining to urine

Further Reading/Sources:

And, of course, Antiquus Morbis

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1865 engraving of Janesville, WI Institute for the Education of the Blind. 

There's a note on another photograph of this school that Louisa May Alcott attended school here, but that made no sense to me...I looked it up, and I don't think Alcott was ever even IN Wisconsin. She certainly didn't go to school at a school for the blind, since she was homeschooled by her father. 

I researched more on the school, and I can't find any notable attendees of it. The only major event or attendee I found was a fire there in 1865 that killed one dude who may have had epilepsy. Am I missing something major? Anyone who's knowledgeable on WI history feel free to let me know...

Fun Fact: Attendees of the school were called "inmates" in the news stories covering the fire.

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Edinburgh School of Anatomy. Anatomy schools in the mid-1800s were finally able to hold the large-group gross anatomy classes that have been almost an initiation rite for medical students since then. Before then, due to religious beliefs and politics, there weren't cadavers available for use by the schools. During the late 18th and through the 19th century, almost all western nations passed laws allowing executed criminals and eventually unclaimed corpses with no known next of kin to be used in schools and for teaching.

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