There is always hope.

biologists will be like this is a very simplified diagram of a mammalian cell

chemists will be like this is a molecule

okay but this is what the best render of a human cell looks like

They are not kidding

We are full of so many fuckign guys

This is actually a full on interactive map! You can put your cursor over any structure to focus on it and see its name, you can focus on all the structures that are part of a specific pathway and, when you click on proteins, you open it up on PhosphoSitePlus, which is a curated database of proteins and their post-translational modifications. It has a helpful description and summary for each protein!

This is a HUGE complementary resource for learning molecular biology! It really helps to make sense of each individual pathway and it puts everything into perspective. It only focuses on human, rat and certain other animal cells, so it won’t have all the pathways one would wish to see… But for the pathways it does include, consider opening the image and accompanying it as you learn or revise them!

oh wow, thank you for the additional information, i had no idea, that’s so much cooler than just the flat picture.

Barbie (2023) // The Good Place (2016-2020)

this looks like the same party

they’re shouting back and forth across the club

I have some much less nice posts currently saved in my drafts that I am clinging on to my self control enough not to post, but I will say this:

This is why you show up and you vote. This is why you show up even when you don't agree with every policy, when you think both candidates are too far to the right, when you think your vote doesn't matter.

We will be spending the next 4+ years living with the consequences of people's decision not to vote or to vote for a third party or to vote for the racist authoritarian rapist felon over an extremely qualified Black/S. Asian woman.

Want a better candidate? Start working on finding and supporting them tomorrow. But in two years, and in four, and in every election in between and after, show up, fulfill your civic responsibility as an American citizen, and vote.

I would vote, but the problem is 1. I live in a state where pretty much everybody and their mother votes for the Democrats anyways, and 2. I don't feel there's much of a point in voting in presidential elections anymore if they're just gonna be decided by a bunch of dickheads in a handful of swing states. Oh, and don't get me started on the assholes in my town who voted for all Rethuglicans for the town council.

I promise that this is not an attack on you, but I want to say a couple of things:

Voting is one of the most low-cost ways that you can express yourself politically. My entire voting experience was somewhere around an hour, and I walk to my polling station. If yours is too far away or election day isn't convenient for you, vote early! Vote by mail! Do whatever is most convenient for you.

But an hour or two of your time (or even four or five) seems like a pretty low cost to have a say in your political representation at the local, state, and federal level.

TIL anyone who's going to overwinter in Antarctica has to have had their appendix out. Because removing an appendix that's not causing any trouble just as a precaution is way better than having one that's about to burst when you're on the ass-end of the planet with no way to be rushed to a hospital if shit gets real.

No, by the way, we absolutely did not think of this ahead of time. A dude named Leonid Rogozov got appendicitis in Antarctica. Fortunately, the expedition's doctor diagnosed him quickly and knew how to remove an appendix. Unfortunately, our man Leo was the expedition's doctor.

What did he do? Well, he set up a mirror, gave his belly a shot of novocaine, presumably told a colleague, "hold my vodka," and he removed his own fucking appendix. He survived.

this picture has such "i lived bitch" energy

yknow what im just leaving this whole tag thread out here

I know most of tumblr is thinking about the USA right now. but fuck the nz government right now too. tomorrow, the treaty principles bill, the 'worst, most comprehensive breach of Te Tiriti in modern times' is being introduced to parliament early, because there were activations planned country wide and the cowards decided to pull it forwards. fuck this government. a friend of mine had to go home early, crying. I've been in shock all day since it came out.

check on your Māori friends, e hoa mā. see what they need. see how you can help. everyday, we see and experience racism. from people around us, up to our government. community care will save us.

I feel like many people have a fundamental misconception of what unreliable narrator means. It's simply a narrative vehicle not a character flaw, a sign that the character is a bad person. There are also many different types of unreliable narrators in fiction. Being an unreliable narrator doesn't necessarily mean that the character is 'wrong', it definitely doesn't mean that they're wrong about everything even if some aspects in their story are inaccurate, and only some unreliable narrators actively and consciously lie. Stories that have unreliable narrators also tend to deal with perception and memory and they often don't even have one objective truth, just different versions. It reflects real life where we know human memory is highly unreliable and vague and people can interpret same events very differently

Some types of unreliable narrator:

The Watson: is present for the event but does not have the same level of perception as protagonist

The Lemony Snicket: isn't present for the event, reconstructs the facts based on later research, can get things wrong or incomplete

The Ted Moseby: is present for the event but has romanticised and embellished their memory of it through nostalgia to an extent that you cannot fully believe it; is also prone to misremembering or outright forgetting details.

The Katniss Everdeen: is present for the event, is the protagonist, but is completely foreign to the world and out of their depth so they don't quite understand a lot of what is going on.

The Rose Quartz: is present for the event, but due to their personal agenda or feelings of shame hides and embellishes what actually happened in favour of a version that paints them in a better light.

The Big Brother: overwrites what actually happened in favour of propaganda.

The Jonathan Harker: is absolutely clueless about what is going on around them and the genre they're in so their perception of events is tinted by their own naivety.

The Goob: the narrator's own emotional bias clouds their judgement of what really happened.

The Tyler Durden: the narrator is suffering from hallucinations and doesn't realise it.

The Pi: the narrator has survived a traumatic experience and copes with it by turning it into a wonderful tale.

Everyone is the unreliable narrator of their own lives.

EVERYONE! IS THE! UNRELIABLE! NARRATOR! OF THEIR OWN LIVES!!

Attention Pennsylvania voters!

Senator Bob Casey’s race is now at a margin of 0.53%.

An automatic recount in PA is triggered with a margin of 0.5%. That’s a difference of 0.03% or a little over 2,000 votes. We need to make sure every ballot is counted here, and there’s thousands of uncounted ballots right now due to voter error.

Did you mail in a ballot? Check to see it was accepted here:

If it says anything other than accepted/counted/etc, your ballot needs your attention. A mistake in filling it out means that your ballot will not count unless you “cure” it. Check your county’s curing policies:

See full instructions for curing by county here.

You have until November 12 to cure your ballot in PA.

Do you know someone who mailed in a PA ballot? Please pass these links on to them. You may be the difference between their vote counting or not in a super close race.

Everyone else, you can help PA voters cure their ballots. If you live in Pennsylvania, you can help canvass in your county (see links in this thread). If you are in another state, you can sign up to call voters and help them cure by phone.

Want to help another state? Sign up for a shift through November 19.

Via Samba's twitter

#so did they miss the part where gatsby ends up floating dead in a pool and all the miserable deaths in wuthering heights#or did they miss that because there weren’t any chapters titled In Which The Sinners Are Punished For Their Errors#like. even if you require explicit moral instruction from literature it’s pretty hard to miss the comeuppance in those.

“What I assume my teachers were trying to teach me”

Huck Finn is about a white Southern boy who was raised to believe that freeing slaves is a sin that would send you directly to hell who forges a familial bond with a runaway slave and chooses to free him and thereby in his mind lose his salvation because he refuses to believe that his best friend and surrogate father is less of a man just because he’s black. Yes it features what we now consider racial slurs but this is a book written only 20 years after people were literally fighting to be allowed to keep other human beings as property, we cannot expect people from the 1880s to exactly conform with the social mores of 2020, and more to the point if we ourselves had been raised during that time period there’s very little doubt that we would also hold most if not all of the prevalent views of the time because actual history isn’t like period novels written now where the heroes are perfect 21st century social justice crusaders and the villains are all as racist and sexist as humanly possible. Change happens slowly and ignoring the radical statement that we’re all human beings that Twain wrote at a time when segregation and racial tensions were still hugely prevalent just because he wrote using the language of his time period is short-sighted and foolhardy to the highest degree.

I’m really kind of alarmed at the rise in the past few years of the “and we do condemn! wholeheartedly!” discourse around historical figures. it seems like people have somehow boomeranged between “morals were different in the past, therefore nobody in the past can ever be held accountable for ANY wrongs” to “morals are universal and timeless, and anything done wrong by today’s standards in the past is ABSOLUTELY unforgiveable” so completely, because social media 2.0 is profoundly allergic to nuance

please try this on for size:

there have always been, in past times as today, a range of people in every society, some of whom were even then fighting for a more just and compassionate accord with their fellow man and some of whom let their greeds and hatreds rule them to the worst allowable excesses. the goal of classics and history education is to teach you enough context to discern between the two, not only in the past but in the present

My mind just boggles at the “There’s Racism In That Book” argument.  Yes, there is racism in that book, because that book is ABOUT RACISM.  The message is that it is BAD. 

My high school English teacher, who was a viciously brilliant woman, used to say that when people banned Huck Finn they said it was about the language, but it was really the message they were trying to ban, the subversive deconstruction of (religious) authority and white supremacy.

Huckleberry Finn can actually be seen as a powerful case study in trying to do social justice when you have absolutely no tools for it, right down to vocabulary.  And in that respect, it’s a heroic tale, because Huck—with absolutely no good examples besides Jim, who he has been taught to see as subhuman, with no guidance, with everyone telling him that doing the right thing will literally damn him, with a vocabulary that’s full of hate speech—he turns around and says, “I’m not going to do it.  I’m not going to participate in this system.  If that means I go to Hell, so be it.  Going to Hell now.”

(I used to read a blogger who insisted that “All right, I’ll go to Hell,” from Huckleberry Finn is the most pure and perfect prayer in the canon of American literature.  Meaning, as I understand it, that the decision to do the right thing in the face of eternal damnation is the most holy decision one can make, and if God Himself is not proud of the poor mixed-up kid, then God Himself is not worth much more than a “Get thee behind me,” and the rest of us should be lining up to go to Hell too.  Worth noting that this person identified as an evangelical Christian, not because he was in line with what current American evangelicals believe, but because “they can change their name, I’m not changing mine.”  Interesting guy.  Sorry for the long parenthetical.)

Anyway, the point of Huck Finn, as far as I can tell, is that you can still choose to do good in utter darkness, with no guidance and no help and none of the right words.

And when you put it like that, it’s no wonder that a lot of people on Tumblr—people who prioritize words over every other form of social justice—find it threatening and hard to comprehend.

do not forget about reservations.

do not forget about the people on reservations.

when you are making and reading posts about dire predictions for quality of life, do not forget about reservations.

we already have issues accessing clean water. we already experience devastation from climate change. we are already going missing for our race. we are already being murdered for our culture.

it will only get worse.

it’s possible to live through. every single person indigenous to north america has a chance to live through this. i’m not trying to fear monger; i’m trying to remind you.

please do not forget about us when you assure people that “everything will be okay; people are living under far worse circumstances in other countries”.

people are living under far worse circumstances here. and it can get worse. and it will get worse. and we need you to remember that we’re here when it happens.

not as punchy, but adding onto this:

What are Indigenous issues that I and the Natives I know are worried about?

- Pipelines affecting water

- Pipelines destroying protected land/land under treaty

- Pipelines are already factually epicenters of the MMIW+ crisis

- Substance abuse and suicide rates

- Directly related to the above, IHS funding

- Tariffs affecting gaming revenue, which is often used significantly in our communities’ funding

- Not a huge systemic issue, but a bummer: no more Native secretary of the interior

- ICWA. holy fuck. ICWA.

- The DoE only being allowed to teach sanitized genocide-denial schlock.

long distance relationship

“I’m afraid of getting cancer from the cadmium in my painting supplies” I’m not 😌 I love you cadmium yellow. I love you vermillion red. I love you uranium orange, haven’t worked with you but I love you nevertheless. Most of all I love you arsenic green.

This dress could kill you but I completely understand why people in the late 19th century were willing to take that risk.

Here is uranium orange fiestaware, proving that beauty truly is pain.

just found out about London purple 🤤

I was wondering what was involved with London purple so as to merit its inclusion alongside such stars as arsenic green and uranium orange, and --

Ah, cool, gotcha

This morning there was a nation-wide text spam campaign targeting Black Americans (largely students) telling them that they’ve been selected to pick cotton and will be picked up to be sent to a plantation after Trump’s inauguration.

People online are making jokes about it, but it’s genuinely a disturbing sign. Someone was emboldened enough to intentionally run a background on thousands of young Black people and send them racist messages the day after a very exhausting and stressful election.

Please boost this if you can!!! This story is still developing and a lot of the people who have been getting the messages say they’re scared to leave home now.

This also happened to students in California; the school district sent out an email about it with support resources. Looks like it was a nation wide thing.

ily, menswear guy